Dennis Lo (1963- )
نویسنده
چکیده
Dennis Lo, also called Yuk Ming Dennis Lo, is a professor at the Chinese University of Hong Kong [5] in Hong Kong, China. In 1997, Lo discovered fetal DNA in maternal plasma, which is the liquid component of a pregnant woman's blood. By 2002, Lo distinguished the DNA differences between pregnant women and their fetuses, enabling scientists to identify fetal DNA in pregnant women's blood. Lo used his discoveries to develop several non-invasive and prenatal genetic tests, including tests for blood group status and Trisomy 21, also called Down's Syndrome. Lo's discovery of fetal DNA in maternal plasma lessened the risks to pregnant women and fetuses during prenatal testing, and it enabled early identification of potential genetic mutations in developing fetuses.
منابع مشابه
Effects of Preanalytical Factors on the Molecular Size of Cell-Free DNA in Blood, K.C
Cell-Free DNA in Blood, K.C. Allen Chan, Sze-Wan Yeung, Wing-Bong Lui, Timothy H. Rainer, and Y.M. Dennis Lo ( Department of Chemical Pathology and 2 Accident and Emergency Medicine Academic Unit, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong Special Administrative Region, China; * address correspondence to this author at: Department of Chemic...
متن کاملOrigin of plasma cell-free DNA after solid organ transplantation.
Transplantation, Yanni Y.N. Lui, Kam-Sang Woo, Angela Y.M. Wang, Chung-Kwong Yeung, Philip K.T. Li, Elaine Chau, Peter Ruygrok, and Y.M. Dennis Lo (Departments of 1 Chemical Pathology, 2 Medicine & Therapeutics, and 3 Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR; 4 Department of Cardiology, Grantham Hospital, Hong Kong SAR; 5 Dep...
متن کاملNoninvasive prenatal exclusion of congenital adrenal hyperplasia by maternal plasma analysis: a feasibility study.
Hyperplasia by Maternal Plasma Analysis: A Feasibility Study, Rossa W.K. Chiu, Tze K. Lau, Pik T. Cheung, Zhi Q. Gong, Tse N. Leung, and Y.M. Dennis Lo (Departments of 1 Chemical Pathology and 2 Obstetrics and Gynaecology, The Chinese University of Hong Kong, Hong Kong SAR; 3 Department of Paediatrics, The University of Hong Kong, Hong Kong SAR; * address correspondence to this author at: Depar...
متن کاملThe Biosynthesis of Thymidylic Acid. v. Hydrogen Isotope Studies with Dihydrofolic Reductase and Thymidylate Synthetase.
The first experiments on hydrogen transfer in the thymidylate synthetase reaction (Equation 1) were reported by Friedkin (2, 3). Borohydride labeled with tritium was used to reduce folic acid to tritium-labeled tetrahydrofolate which was then treated with formaldehyde to yield the 5, lo-methylene derivative. When the latter compound was used as substrate for thymidylate synthetase (prepared fro...
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